Clinical Advisors

Emmanuel Antonarakis, MD

Johns Hopkins University

Emmanuel Antonarakis, MD, is a Professor of Oncology and Urology at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center. He obtained his medical degree from the University of Wales College of Medicine (United Kingdom) in 2003, and then completed a Residency in Internal Medicine at the Johns Hopkins Bayview Medical Center, followed by a Fellowship in Medical Oncology at the Johns Hopkins Hospital. In 2010, he joined the Johns Hopkins faculty as an attending physician and translational researcher. Dr. Antonarakis’ clinical interest is the management of prostate cancer and other genitourinary malignancies.

His research focuses on drug development and clinical trial design for patients with prostate cancer. More specifically, he is interested in developing novel androgen-directed therapies as well as immunotherapies for men with recurrent or advanced prostate cancer and using cancer genomics to inform precision oncology approaches. He also has an interest in biomarker development, specifically the clinical validation of the AR-V7 biomarker as well as DNA repair markers and their therapeutic implications. He is currently the Pl of several phase II and Ill prostate cancer trials, and is an active member of the Prostate Cancer Clinical Trials Consortium (PCCTC) and the Eastern Cooperative Oncology Group (ECOG) as well as the NCI Prostate Cancer Task Force. He serves on the Editorial Board of several oncology journals, including the Journal of Clinical Oncology. He is the author of over 220 peer-reviewed articles, and several book chapters.